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Blade angle Angle (Degrees) 498 Epithelial tumors sulfate Sulfatase androstendione Estrogen Pathway EGF Pathway APC Pathway estrone estradiol ER EGF EGFR RAS cell growth Prolactin ARHI PI3-K PKB mTOR anti-apoptosis CYP19A1 PKB NCOA3 CBP Cyclin D1 IGF RAF MEK ERK APC β-Catenin TCF cell growth cell growth autocrine factors TGFα IGF-1 IGF-2 Figure 15.

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